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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76013 | Carbonic anhydrase | ||
Carbonic anhydrase is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase... | |||
T77631 | Enpp/Carbonic anhydrase-IN-2 | Apoptosis , PDE , Carbonic Anhydrase | |
Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-I... | |||
T67775 | Enpp/Carbonic anhydrase-IN-1 | PDE , Carbonic Anhydrase | |
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectiv... | |||
T63305 | Carbonic anhydrase inhibitor 6 | ||
Carbonic anhydrase inhibitor 6 is a potent inhibitor of human carbonic anhydrase (hCA), acting on hCA IX (Ki: 9.7 nM), hCA II (Ki: 35.2 nM), hCA XII (Ki: 88.5 nM) and hCA I (Ki: 91.8 nM). | |||
T0515 | Tioxolone | Carbonic Anhydrase | |
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor. | |||
T16960 | Sultiame | Others , Carbonic Anhydrase | |
Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research. | |||
T8827 | EMAC10101d | Carbonic Anhydrase | |
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range. | |||
T0142 | Brinzolamide | AL-4862 | Carbonic Anhydrase |
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor. | |||
T0782 | Benzthiazide | Aquatag,Lemazide,Dihydrex | Carbonic Anhydrase |
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ... | |||
T4321 | Indisulam | E 7070 | CDK , Carbonic Anhydrase |
Indisulam (E 7070) is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in th... | |||
T6781 | Benzenesulfonamide | Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide | Carbonic Anhydrase |
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases. | |||
T60848 | Carbonic anhydrase inhibitor 3 | ||
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1]. | |||
T78840 | Carbonic anhydrase inhibitor 15 | Carbonic Anhydrase | |
Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1]. | |||
T2187 | Orthanilamide | O-Aminobenzenesulfonamide,Benzenesulfonamide,O-Sulfanilamide | Carbonic Anhydrase , Autophagy |
Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline. | |||
T4S2354 | Dimethylfraxetin | Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin | Carbonic Anhydrase |
Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM) | |||
T61120 | Carbonic anhydrase inhibitor 2 | ||
Compound 7c, identified as carbonic anhydrase inhibitor 1, effectively inhibits carbonic anhydrase II. This inhibitor, also known as carbonic anhydrase inhibitor 3, lowers intraocular pressure in glaucomatous rabbits [1]... | |||
T61952 | Carbonic anhydrase inhibitor 13 | ||
Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA). | |||
T61829 | Carbonic anhydrase inhibitor 4 | ||
Carbonic anhydrase inhibitor 4 is a photoprobe that inhibits the activity of carbonic anhydrase. It specifically targets human carbonic anhydrases, including hCA I-XIV, with K i values ranging from 640-1166 nM [1]. | |||
T61980 | Carbonic anhydrase inhibitor 8 | ||
Carbonic anhydrase inhibitor 8 (compound R-13) is a potent human carbonic anhydrase (hCA). Carbonic anhydrase inhibitor 8 shows K i values of 60.7 nM, 320.7 nM, 2298 nM for hCA I, hCA II, hCA IV, respectively. | |||
T63731 | Carbonic anhydrase inhibitor 9 | ||
Carbonic anhydrase inhibitor 9 is a potent inhibitor of carbonic anhydrase (CA) that acts on hCA II (Ki: 56.4 nM) and IX (Ki: 56.9 nM) and exhibits antiproliferative effects. |